DOI: https://doi.org/10.37987/1997-9894.2020.1 (237).214171

Сучасні аспекти лікування гіпертонічної хвороби, поєднаної з ішемічною хворобою серця

S. A. Bondarchuk, О. G. Andrievsky

Анотація


Ішемічна хвороба серця (ІХС) залишається головною причиною смертності та захворюваності у світі, до категорії особливо високого ризику належать пацієнти з гіпертонічною хворобою (ГХ). Як відомо, високий артеріальний тиск (АТ) у пацієнтів – один із найважливіших факторів серцево-судинного ризику, який можна модифікувати. Досягнення оптимальних рівнів АТ у цій популяції пацієнтів приводить до зни-ження ризику небажаних подій, однак надмірне зниження АТ може призводити до зниження міокардіальної та церебральної перфузії, існує залежність у пацієнтів з крайніми цифрами артеріального тиску (АТ) у вигляді J-кривої. У статті проведено аналіз даних досліджень пацієнтів з ІХС та ГХ залежно від різних цільових рівнів зниження АТ у світлі нових рекомендацій на тлі медикаментозної терапії.


Ключові слова


ішемічна хвороба серця; гіпертонічна хвороба; антигіпертензивні засоби; цільовий артеріальний тиск; феномен J-кривої; несприятливі серцево-судинні події; кінцеві точки

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Особливості ведення пацієнтів з артеріальною гіпертензією і коморбідними станами сімейними лікарями (з урахуванням Європейських рекомендацій 2018 року) : методичні рекомендації / М. М. Долженко, І. В. Давидова, В. А. Несукай та співавт. – Київ, 2018.


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